缍�(w菐ng)鏍＄偤浜嗘柟渚垮唬澶у(xu茅)鍝℃湁鏁堝倷鑰�2008骞村煼(zh铆)妤�(y猫)钘ュ斧鑰冭│锛岀壒鎰忔暣鐞嗕簡2008鍩�(zh铆)妤�(y猫)钘ュ斧钘ョ墿鍒嗘瀽缍滃悎瑭﹂鍙婄瓟妗�锛屽笇鏈涢€欎唤2008鍩�(zh铆)妤�(y猫)钘ュ斧钘ョ墿鍒嗘瀽缍滃悎瑭﹂鍙婄瓟妗堣兘澶犲公鍔╁ぇ瀹舵洿濂界殑寰�(f霉)缈�(x铆)锛屼互渚块€氶亷(gu貌)姝ゆ鐨勮€冭│銆�

銆€銆€绛旓細鍘熺悊锛�

銆€銆€鍦ㄩ仼鐣�(d膩ng)?sh霉)鎱曟|(zh矛)涓�锛岀敓鐗╁牽椤�(l猫i)钘ョ墿鍙垏姘洟瀛愮祼(ji茅)鍚堢敓鎴愮敓鐗╁牽闄�(y谩ng)闆㈠瓙锛屼竴浜涢吀鎬х噧鏂欏婧寸櫨閲岄厷钘�(l谩n)銆佹捍閰氳棈(l谩n)绛夊彲瑙ｉ洟鎴愰櫚闆㈠瓙锛岃€屼笂杩伴櫧(y谩ng)闆㈠瓙鑸囬櫚闆㈠瓙瀹氶噺绲�(ji茅)鍚堟垚鏈夋(j墨)绲�(lu貌)鍚堢墿锛屽嵆闆㈠瓙灏�(du矛)銆傚彲浠ュ畾閲忕殑鐢ㄦ湁姗�(j墨)婧跺姂鎻愬彇锛屽湪涓€瀹氱殑娉㈤暦(zh菐ng)铏曟脯(c猫)瀹氳┎婧舵恫鏈夎壊闆㈠瓙灏�(du矛)鐨勫惛鏀跺害锛屽嵆鍙▓(j矛)绠楀嚭鐢熺墿鍫跨殑鍚噺銆�

銆€銆€娉ㄦ剰浜嬮爡(xi脿ng)锛�

銆€銆€锛�1锛夋按鐩告渶浣硃H鍊肩殑閬告搰

銆€?銆�?锛夐吀鎬ф煋鏂欑殑閬告搰

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銆€銆€1.鍙栨(bi膩o)绀洪噺鐐�100mg鐨勭暟鐓欒偧鐗�20鐗�锛岀ū(ch膿ng)寰楄唱(zh矛)閲忕偤2.422g锛岀爺绱�(x矛)鍚�锛岀簿瀵嗙ū(ch膿ng)鍙栫墖绮�0.2560g锛岀疆100ml閲忕摱涓�锛屽姞姘撮仼閲�锛屾尟鎼栦娇鐣扮厵鑲兼憾瑙ｅ苟绋€閲嬪埌鍒诲害锛屾悥鍕�锛岀敤骞茬嚗婵剧礄婵鹃亷(gu貌)锛岀簿瀵嗛噺鍙栫簩(x霉)婵炬恫25ml锛屽姞姘�50ml锛岄菇閰�20ml鑸囩敳鍩烘鎸囩ず鍔�1婊�锛岀敤婧撮吀閴€婊村畾娑诧紙0.01667mol/L锛夋淮瀹氾紝鑷崇矇绱呰壊娑堝け锛屾秷鑰�16.10ml.姣�1ml鐨勬捍閰搁墍婊村畾娑诧紙0.01000mol/L锛夌浉鐣�(d膩ng)浜�2.057mg鐨勭暟鐓欒偧銆傝▓(j矛)绠楃暟鐓欒偧鐨勬(bi膩o)绀洪噺鐧惧垎鍚噺銆�

銆€銆€瑙ｏ細渚涜│鍝佹(bi膩o)绀洪噺鐧惧垎鍚噺鐐�104.5%

銆€銆€2銆佺従(xi脿n)鏈夋(bi膩o)绀洪噺鐐�25000IU/涓哥殑婵冪府榄�(y煤)鑲濇补涓革紙骞冲潎涓搁噸0.200g锛夌ū(ch膿ng)鍙栨ǎ鍝�0.1600g锛屾憾浜庣挵(hu谩n)宸辩兎骞剁█閲嬫垚2500鍊嶅悗锛屼簬涓嬪垪娉㈤暦(zh菐ng)鍒嗗垾娓�(c猫)瀹氬惛鏀跺害濡備笅锛岃│瑷�(j矛)绠楀叾鍚噺锛圛U/涓革級鐩哥暥(d膩ng)浜庢(bi膩o)绀洪噺鐨勭櫨鍒�?j菒n)?sh霉)銆�

銆€銆€娉㈤暦(zh菐ng)锛坣m锛夈€€銆€銆€銆€娓�(c猫)寰楀惛鏀跺害銆€銆€銆€銆€銆€钘ュ吀瑕�(gu墨)瀹氱殑鍚告敹搴︽瘮鍊�

銆€銆€300銆€銆€銆€銆€銆€銆€銆€銆€0.250銆€銆€銆€銆€銆€銆€銆€銆€0.555

銆€銆€316銆€銆€銆€銆€銆€銆€銆€銆€0.376銆€銆€銆€銆€銆€銆€銆€銆€0.907

銆€銆€328銆€銆€銆€銆€銆€銆€銆€銆€0.438銆€銆€銆€銆€銆€銆€銆€銆€1.000

銆€銆€340銆€銆€銆€銆€銆€銆€銆€銆€0.380銆€銆€銆€銆€銆€銆€銆€銆€0.811

銆€銆€360銆€銆€銆€銆€銆€銆€銆€銆€0.136銆€銆€銆€銆€銆€銆€銆€銆€0.299

銆€銆€闄勬敞锛氾紙1锛夎棩鍏歌(gu墨)瀹氱殑鍚告敹搴︽瘮鍊硷紙瑕�(ji脿n)涓婅〃锛�

銆€?銆�?锛夋牎姝ｅ叕寮廇328锛堟牎姝ｅ悗锛�=3.52锛�2A328锛岮316锛岮340锛�

銆€銆€瑙ｏ細鏍规摎(j霉)椤屾剰锛岃▓(j矛)绠楀悇娉㈤暦(zh菐ng)铏曞惛鏀跺害鑸�328nm娉㈤暦(zh菐ng)铏曞惛鏀跺害鐨勬瘮鍊硷紝骞惰垏瑕�(gu墨)瀹氭瘮鍊兼瘮杓�

娉㈤暦(zh菐ng)nm  300  316  328  340  360 
鍚告敹搴︽瘮鍊� 锛圓i/A328锛�  0.571  0.858  1  0.868  0.311 
瑕�(gu墨)瀹氭瘮鍊�  0.555  0.907  1  0.811  0.299 
姣斿€间箣宸�  0.016  -0.049  0  0.057  0.012 

銆€?銆�?鍒嗭級

銆€銆€鍏朵腑锛屾瘮鍊糀(ch菙)316/A328銆丄340/A328鑸囪(gu墨)瀹氭瘮鍊间箣宸秴閬�(gu貌)闄愬害锛埪�0.02锛�锛屾晠闇€瑷�(j矛)绠楁牎姝ｅ惛鏀跺害锛屽苟鑸囧(sh铆)娓�(c猫)鍊兼瘮杓冿紙1鍒嗭級

銆€銆€A328锛堟牎姝ｅ悗锛�=3.52锛�2A328锛岮316锛岮340锛�

銆€銆€銆€銆€銆€銆€銆€銆€銆€= 3.52锛�2脳0.438-0.376-0.38锛�

銆€銆€銆€銆€銆€銆€銆€銆€銆€=0.4224 锛�1鍒嗭級

銆€?銆偹�328锛堟牎姝ｅ悗锛�- A328锛�/ A328 = 锛�0.4224- 0.438锛�/0.438 = -0.036 锛�1鍒嗭級

銆€銆€鏍℃鍚告敹搴﹁垏瀵�(sh铆)娓�(c猫)鍊间箣宸凡瓒呴亷(gu貌)瀵�(sh铆)娓�(c猫)鍊肩殑-3%锛屾晠鎳�(y墨ng)浠328锛堟牎姝ｏ級瑷�(j矛)绠楀惈閲�銆傦紙1鍒嗭級

銆€銆€瑷�(j矛)绠椾緵瑭﹀搧鐨勫惛鏀剁郴鏁�(sh霉)锛�328nm锛夊€�

銆€銆€328nm = A328锛堟牎姝ｅ悗锛�/ 锛�100ms/D 锛�

銆€銆€銆€銆€銆€= 0.4224/锛�100脳0.1600/2500锛�

銆€銆€銆€銆€銆€= 66 锛�1鍒嗭級

銆€銆€渚涜│鍝佷腑缍敓绱燗鏁堝児(ji脿)= 328nm 脳 1900

銆€銆€銆€銆€銆€銆€銆€銆€銆€銆€銆€銆€= 66 脳 1900

銆€銆€銆€銆€銆€銆€銆€銆€銆€銆€銆€銆€= 125400 锛圛U/g锛�

銆€銆€

銆€銆€銆€銆€銆€銆€= 125400脳 0.200/25000 脳 100%

銆€銆€銆€銆€銆€銆€= 100.32% 锛�1鍒嗭級

銆€銆€绛旓細渚涜│鍝佹(bi膩o)绀洪噺鐧惧垎鍚噺鐐�100.32%

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钘ヤ簨绠＄悊鑸囨硶瑕�(gu墨)	鏈� 闈� 姹� 婵�	40		20		3濂�		鍫�(b脿o)鍚�
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